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Drugs for PUD

by drdasaraju
April 29, 2022August 21, 2024

All the following are class of drugs for peptic ulcer disease due to H.pylori, except

Cytoprotective agents

Na+/K+ ATPase inhibitors

Antibacterial agents

H2 receptor antagonists

None

All the following are true regarding H2 receptor antagonists, except

Administered orally as well as parenterally

Ranitidine is an example

Drug interactions are more common with famotidine

Long term usage may result in hypergastrinaemia

None

All the following are true regarding proton pump inhibitors, except

Long term usage increases the risk of bone fractures

Pantoprazole is an example

Inhibits the H+-K+-ATPase reversibly

Drug interactions are more common with omeprazole

None

All the following are true regarding antacids, except

Magnesium salts in antacids cause diarrhoea

Affect the bioavailability of some drugs

Acid-neutralization capacity among different antacids is same

Are weak bases that react with gastric HCl to form a salt and water

None

All the following are true regarding sucralfate, except

Acts as a cytoprotective agent

Co-administered with antacids increases its efficacy

Constipation is an important adverse effect

Complex of aluminium hydroxide and sulfated sucrose

None

All the following are true regarding bismuth, except

Safe to give in renal failure patients

Blackening of the tongue is an important adverse effect

Has the advantage of offering lower rate of relapse in peptic ulcer

Prevents the adherence of H. pylori to gastric mucosa

None

All the following are true regarding misoprostol, except

Given orally to prevent gastric ulcers due to NSAIDs

Increase the secretion of mucus and bicarbonate

Analogue of prostaglandin I (PGI)

Diarrhoea is the common adverse effect

None

Time's up

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