Drugs for Malaria

Which of the following drug is effective in eradicating P. vivax and P. ovale parasites in the liver?

Chloroquine

Primaquine

Artemisine

Lumefantrine

All the following drugs are effective in eradicating P. falciparum parasites in the blood, except

Quinine

Atovaquone

Mefloquine

Tafenoquine

All the following drugs are effective in preventing malaria transmission by acting on gametocytes, except

Primaquine

Artemether

Proguanil

Pyrimethamine

All the following are true regarding artemisinin derivatives, except

Fast-acting blood schizonticides

Considered to be safe in pregnant women

Available as oral and parenteral preparations

Effective against chloroquine-resistant and cerebral malaria

All the following are true regarding chloroquine, except

Available as oral and intravenous preparations

Effective against the erythrocytic forms of all plasmodial species

Acts by inhibiting haem polymerase

Should not be used in pregnant women

All the following are true regarding quinine, except

Has no effect on exoerythrocytic forms of plasmodial species

Considered to be safe in the 1st trimester of pregnancy

Bolus intravenous administration is recommended for severe P. falciparum infections

Associated with hypoglycemia

All the following are true regarding primaquine, except

Tafenoquine is a long acting analogue of primaquine

Ineffective against the erythrocytic stage of the plasmodia

Glucose 6-phosphate dehydrogenase activity should be estimated before giving the drug

Available as oral and intravenous preparations

Which of the antimalarial drug is least associated with resistance?

Chloroquine

Artemether

Primaquine

Lumefantrine

All the following antibacterial drugs are effective against treatment of malaria, except

Doxycycline

Sulfamethoxazole

Dapsone

Clindamycin

Antimalarial drug indicated for short term chemoprophylaxis (stay upto 6 weeks) is

Chloroquine

Primaquine

Doxycycline

Clindamycin

Antimalarial drug indicated for long term chemoprophylaxis (stay > 6 weeks) is

Sulphadoxine

Proguanil

Atovaquone

Mefloquine

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